ParkinsonV1, Main, Exploration, bibRecord, 002753

Slowing of high-speed memory scanning in Parkinson's disease is related to the severity of parkinsonian motor symptoms

Identifieur interne : 002753 ( Main/Exploration ); précédent : 002752; suivant : 002754

Slowing of high-speed memory scanning in Parkinson's disease is related to the severity of parkinsonian motor symptoms

Auteurs : G. Ransmayr [Autriche] ; W. Bitschnau [Autriche] ; B. Schmidhuber-Eiler [Autriche] ; W. Berger [Autriche] ; E. Karamat [Autriche] ; Werner Poewe [Autriche] ; W. Kemmler [Autriche]

Source :

Journal of Neural Transmission - Parkinson's Disease and Dementia Section [ 0936-3076 ] ; 1990-12-01.

RBID : ISTEX:20BE50ACC3D4B0C9DE226D7689165336DBD1B5E6

Abstract

Summary: High-speed memory scanning (Sternberg paradigm) was tested in a collective of 20 parkinsonian patients (10 newly diagnosed, untreated patients, duration of the disease 0.5–3.8, mean 1.5 years; 10 levodopa-treated patients, duration of the disease 4.2 to 11, mean 7.6 years). The levodopa-treated patients stopped taking levodopa before the test. There was a tendency towards retarded memory scanning in the patients' collective compared with 20 healthy controls with similar ages and verbal IQs (p=0.076, Mann-Whitney U test). The mental slowing correlated significantly with bradykinesia and the sum-score of the Columbia University Parkinson Rating Scale (p=0.021 and 0.019; Spearman rank correlation). Kruskal-Wallis ANOVA revealed a significant mental slowing in the subgroup of patients with Parkinson's disease for >4 years compared with the newly diagnosed patients and the controls (H=8.54; p=0.019 and 0.006, Mann-Whitney U test). The findings suggest a mental slowing in Parkinson's disease, which is associated with the progression of parkinsonian motor symptoms and not with depression.

Url:

https://api.istex.fr/document/20BE50ACC3D4B0C9DE226D7689165336DBD1B5E6/fulltext/pdf

DOI: 10.1007/BF02252921

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Summary: High-speed memory scanning (Sternberg paradigm) was tested in a collective of 20 parkinsonian patients (10 newly diagnosed, untreated patients, duration of the disease 0.5–3.8, mean 1.5 years; 10 levodopa-treated patients, duration of the disease 4.2 to 11, mean 7.6 years). The levodopa-treated patients stopped taking levodopa before the test. There was a tendency towards retarded memory scanning in the patients' collective compared with 20 healthy controls with similar ages and verbal IQs (p=0.076, Mann-Whitney U test). The mental slowing correlated significantly with bradykinesia and the sum-score of the Columbia University Parkinson Rating Scale (p=0.021 and 0.019; Spearman rank correlation). Kruskal-Wallis ANOVA revealed a significant mental slowing in the subgroup of patients with Parkinson's disease for >4 years compared with the newly diagnosed patients and the controls (H=8.54; p=0.019 and 0.006, Mann-Whitney U test). The findings suggest a mental slowing in Parkinson's disease, which is associated with the progression of parkinsonian motor symptoms and not with depression.</div>
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Slowing of high-speed memory scanning in Parkinson's disease is related to the severity of parkinsonian motor symptoms

Slowing of high-speed memory scanning in Parkinson's disease is related to the severity of parkinsonian motor symptoms

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri